– We find a reasonable correlation involving hospitals and primary Health care. When the usage of one particular opioid raises in hospitals, we often see the same trend between standard practitioners.
An additional vital locating is that basic practitioners are accountable for almost 90% of opioid prescriptions in Norway.
Sammenlignet med bruken av morfin, økte forskrivingen av oksykodon i Norge betydelig fra 2010 til 2021. Det viser en studie som ble publisert i European Journal of Pain i juli i år.
Det er ingen nasjonale norske retningslinjer som anbefaler legene å bruke morfin fremfor oksykodon. Norsk legemiddelhåndbok anbefaler morfin ved valg av sterke opioidagonister.
Men dette er et vanskelig bilde, for det finnes jo også mange andre smertestillende legemidler enn morfin og oksykodon. Grunnen til at vi valgte disse to er at de er ganske like, brukes ofte til det samme og derfor er mest sammenlignbare og very best egnet til å kunne si noe statistisk om sammenhengen mellom bruken på sykehus og i sykehusenes opptaksområder.
– We see an important rise in the usage of oxycodone through the entire healthcare method, even though the usage of morphine is declining in Key Health care and only raising a little bit in hospitals, clarifies direct writer Eirik Haarr from your University of Stavanger and KORFOR.
Summary Qualifications: Rising oxycodone prescribing and its association with opioid-similar harms have lifted problems. In Norway, approximately ninety% of opioids are prescribed in Key treatment, making primary care decisions crucial to Over-all opioid publicity. In-hospital use may possibly impact Main care procedures as a result of a number of mechanisms. This examine analyses oxycodone and morphine use in Norwegian hospitals and its association with Principal care prescribing from 2010 to 2021, along with a review of tender agreements for these drugs. Procedures: Morphine and oxycodone, out there in all applicable formulations, served as opioid proxies to check covariation amongst hospitals and their catchment areas. We analyzed 2010-2021 procurement details from medical center pharmacies and primary care dispensing data with the Norwegian Prescription Database for all hospital trusts. Correlations among medical center and primary care morphine-to-oxycodone prescribing ratios had been assessed making use of Pearson's r. Annual tender agreements had been received through the national Medical center Procurement Organization. Benefits: Healthcare facility oxycodone use elevated by 67.0% and primary care prescribing rose by 86.five%. Morphine use elevated by 12.6% in hospitals but lowered by 23.
Et par artikler har antydet av oksykodon kan være mer avhengighetsskapende, Males så langt finnes det ingen randomiserte studier som har kunnet si noe mer sikkert. Jeg tror markedsføringen er én ting. Noe annet er manglende nasjonale retningslinjer og at det derfor blir opp til den enkelte legen å velge, svarer Haarr.
The general goal of The purpose challenge is to deliver know-how to enhance remedy of patients with Serious soreness as a way to stay away from pointless escalation of opioid treatment, enrich patients' Standard of living, and lessen the ailment burden.
– Jeg har nylig hatt kontakt med to uavhengige anestesiavdelinger som er i en prosess med å skifte til mer morfin og mindre oksykodon. Det at andre faginstanser tenker i samme baner støtter også vår anbefaling.
Last but not least, the researchers issue to the necessity for a better comprehension of how the procurement method and drug availability have here an affect on real prescribing designs.
Final results Clinic oxycodone use enhanced by sixty seven.0% and primary care prescribing rose by 86.five%. Morphine use amplified by twelve.6% in hospitals but lowered by 23.2% in primary treatment. A reasonable covariation (Pearson's r = 0.48) among clinic use and primary care prescribing was noticed. Medical center tender agreements for morphine declined by 80%, while All those for oxycodone remained stable. Conclusions Oxycodone use considerably improved relative to morphine in Norwegian hospitals and first treatment. Prescription patterns demonstrate average covariation, suggesting a possible hyperlink amongst healthcare facility and first treatment prescribing, though causality remains unsure. Tender agreements may add to prescribing traits in hospitals, with possible associations in Main care. Importance This examine is the first to deliver quantitative evidence of covariation among in-clinic use and first treatment opioid prescribing across a countrywide healthcare system. In spite of tips favoring morphine, oxycodone prescribing carries on to increase in Norway, with marked geographical variation. By linking procurement facts, prescription patterns and tender agreements, our results emphasize the need to take into consideration clinic tactics and structural aspects when addressing opioid prescribing. These effects offer new insights into likely levers for opioid stewardship throughout care degrees.
Forskerne har analysert utviklingen i bruk av morfin og oksykodon i perioden 2010 til 2021. Samtidig har de undersøkt om endringer i bruken av disse to stoffene i sykehus kan henge sammen med utviklingen i primærhelsetjenesten.
En ny studie fra POINT-prosjektet og KORFOR viser at bruken av det sterke smertestillende opioidet oksykodon har økt betydelig i norske sykehus og primærhelsetjenesten de siste ti årene. Studien er publisert i European Journal of Agony.